Congenital Diaphragmatic Hernia (CDH)
Congenital diaphragmatic hernia (CDH) is defined as defect/ a hole in the diaphragm muscle (the muscle that separates the chest from the abdomen) . Diaphragm fails to close during prenatal development, and the contents from the abdomen (stomach, intestines and/or liver) migrate into the chest through this hole/ defect.
Its incidence is 1 in every 2,500 live births.
The herniation of the abdominal organs in the chest prevents the lungs development, resulting in pulmonary hypoplasia (or underdeveloped lungs). This can cause reduced blood flow to the lungs and pulmonary hypertension (high blood pressure in the pulmonary circulation), as well as asthma, gastrointestinal reflux, feeding disorders and developmental delays.
CDH can occur mostly on the left side (80%), right side(20%) or, very rarely, on both sides. It can be life-threatening.